SB225002
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | SB225002 is a potent, and selective CXCR2 antagonist with IC50 of 22 nM for inhibiting interleukin IL-8 binding to CXCR2, > 150-fold selectivity over the other 7-TMRs tested. | ||
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Catalog Num | A14209 |
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Formula | C13H10BrN3O4 |
Molecular Weight | 352.14 |
CAS Number | 182498-32-4 |
SMILES | C1=CC=C(C(=C1)NC(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])O)Br |
Synonyms | SB-225002, SB 225002 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 64 mg/mL (181.74 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 3 mg/mL (8.51 mM) | ||
In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 28.4 mL | 141.99 mL | 283.98 mL |
0.5 mM | 5.68 mL | 28.4 mL | 56.8 mL |
1 mM | 2.84 mL | 14.2 mL | 28.4 mL |
5 mM | 0.57 mL | 2.84 mL | 5.68 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2