CTEP

Catalog No.: A11968
CTEP is a highly potent, selective and orally bioavailable allosteric antagonist of mGlu5 receptor with an IC50 of 2.2 nM.
Grouped product items
Product Name Price Stock Qty
CTEP 5mg
$100.00
In stock
CTEP 10mg
$180.00
In stock
CTEP 50mg
$700.00
In stock
CTEP 10mM * 1mL in DMSO
$120.00
In stock
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Biological Activity
Discription CTEP is a highly potent, selective and orally bioavailable allosteric antagonist of mGlu5 receptor with an IC50 of 2.2 nM.
Targets
Target Value
Product Information
Catalog Num A11968
Formula C19H13ClF3N3O
Molecular Weight 391.77
CAS Number 871362-31-1
SMILES CC1=C(N=C(N1C2=CC=C(C=C2)OC(F)(F)F)C)C#CC3=CC(=NC=C3)Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 76 mg/mL (193.99 mM)
Water Insoluble
Ethanol 10 mg/mL (25.52 mM)
In vivo 2% DMSO+40% PEG 300+2% Tween 80+ddH2O 8 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.53 mL 127.63 mL 255.25 mL
0.5 mM 5.11 mL 25.53 mL 51.05 mL
1 mM 2.55 mL 12.76 mL 25.53 mL
5 mM 0.51 mL 2.55 mL 5.11 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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