Pimecrolimus
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Pimecrolimus is a natural ascomycin macrolactam that binds to macrophilin-12 (FKBP-12) and inhibits calcineurin as well as prolyl isomerase (rotamase). |
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Catalog Num | A10732 |
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Formula | C43H68ClNO11 |
Molecular Weight | 810.5 |
CAS Number | 137071-32-0 |
SMILES | CC[C@@H]1/C=C(\C[C@@H](C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC1=O)O)C)/C(=C/[C@@H]4CC[C@@H]([C@@H](C4)OC)Cl)/C)O)C)OC)OC)C)/C |
Synonyms | Elidel, SDZ-ASM-981 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 94 mg/mL (115.98 mM) | |
Water | Insoluble | ||
Ethanol | 94 mg/mL (115.98 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 12.34 mL | 61.69 mL | 123.38 mL |
0.5 mM | 2.47 mL | 12.34 mL | 24.68 mL |
1 mM | 1.23 mL | 6.17 mL | 12.34 mL |
5 mM | 0.25 mL | 1.23 mL | 2.47 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2