S/GSK1349572 (Dolutegravir)

Catalog No.: A11068
HIV integrase inhibitor
S/GSK1349572 is a potent next generation HIV integrase inhibitor and demonstrates a superior resistance profile substantiated with 60 integrase mutant molecular clones.
Grouped product items
Product Name Price Stock Qty
S/GSK1349572 5mg
$75.00
In stock
S/GSK1349572 10mg
$125.00
In stock
S/GSK1349572 50mg
$315.00
In stock
S/GSK1349572 100mg
$495.00
In stock
S/GSK1349572 10mM * 1mL in DMSO
$120.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's S/GSK1349572 (Dolutegravir) has been cited by 1 publications
  • Lea El Khoury, .et al. , PeerJ Preprints, 2019, 7:e27833v1
  • Biological Activity
    Discription S/GSK1349572 is a potent next generation HIV integrase inhibitor and demonstrates a superior resistance profile substantiated with 60 integrase mutant molecular clones.
    Targets
    Target Value
    Product Information
    Catalog Num A11068
    Formula C20H19F2N3O5
    Molecular Weight 419.4
    CAS Number 1051375-16-6
    SMILES C[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O
    Synonyms Dolutegravir, GSK-1349572
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO Warmed: 71 mg/mL (169.3 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.84 mL 119.22 mL 238.44 mL
    0.5 mM 4.77 mL 23.84 mL 47.69 mL
    1 mM 2.38 mL 11.92 mL 23.84 mL
    5 mM 0.48 mL 2.38 mL 4.77 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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