Monastrol

Catalog No.: A11976
Kinesin-5(KIF11) inhibitor
Monastrol is a potent, cell permeable non-tubulin-interacting mitosis inhibitor. Monastrol blocks mitosis (IC5N/A = 14 μM) by binding to the mitotic kinesin Eg5, a motor protein required for spindle bipolarity.
Grouped product items
Product Name Price Stock Qty
Monastrol 5mg
$80.00
In stock
Monastrol 10mg
$110.00
In stock
Monastrol 25mg
$230.00
In stock
Monastrol 50mg
$390.00
In stock
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Biological Activity
Discription Monastrol is a potent, cell permeable non-tubulin-interacting mitosis inhibitor. Monastrol blocks mitosis (IC5N/A = 14 μM) by binding to the mitotic kinesin Eg5, a motor protein required for spindle bipolarity.
Targets
Target Value
Product Information
Catalog Num A11976
Formula C14H16N2O3S
Molecular Weight 292.4
CAS Number 329689-23-8
SMILES CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 54 mg/mL (184.71 mM)
Water Insoluble
Ethanol 54 mg/mL (184.71 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.2 mL 171 mL 342 mL
0.5 mM 6.84 mL 34.2 mL 68.4 mL
1 mM 3.42 mL 17.1 mL 34.2 mL
5 mM 0.68 mL 3.42 mL 6.84 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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