CTEP
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | CTEP is a highly potent, selective and orally bioavailable allosteric antagonist of mGlu5 receptor with an IC50 of 2.2 nM. | ||
---|---|---|---|
Targets |
|
Catalog Num | A11968 |
---|---|
Formula | C19H13ClF3N3O |
Molecular Weight | 391.77 |
CAS Number | 871362-31-1 |
SMILES | CC1=C(N=C(N1C2=CC=C(C=C2)OC(F)(F)F)C)C#CC3=CC(=NC=C3)Cl |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 76 mg/mL (193.99 mM) | |
Water | Insoluble | ||
Ethanol | 10 mg/mL (25.52 mM) | ||
In vivo | 2% DMSO+40% PEG 300+2% Tween 80+ddH2O | 8 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 25.53 mL | 127.63 mL | 255.25 mL |
0.5 mM | 5.11 mL | 25.53 mL | 51.05 mL |
1 mM | 2.55 mL | 12.76 mL | 25.53 mL |
5 mM | 0.51 mL | 2.55 mL | 5.11 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2