Cerdulatinib

Catalog No.: A14210
multi-targeted tyrosine kinase inhibitor
Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively.
Grouped product items
Product Name Price Stock Qty
Cerdulatinib 10mg
$90.00
In stock
Cerdulatinib 25mg
$200.00
In stock
Cerdulatinib 50mg
$350.00
In stock
Cerdulatinib 10mM * 1mL in DMSO
$102.00
In stock
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Biological Activity
Discription Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively.
Targets
Target Value
Product Information
Catalog Num A14210
Formula C20H28ClN7O3S
Molecular Weight 482
CAS Number 1369761-01-2
SMILES CCS(=O)(=O)N1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4CC4)C(=O)N.Cl
Synonyms PRT062070, PRT2070, PRT-2070
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO Warmed: 42 mg/mL (87.14 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+corn oil 2 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.75 mL 103.73 mL 207.47 mL
0.5 mM 4.15 mL 20.75 mL 41.49 mL
1 mM 2.07 mL 10.37 mL 20.75 mL
5 mM 0.41 mL 2.07 mL 4.15 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

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    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2

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