Cilengitide

Catalog No.: A12372
Integrin inhibitor
Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.
Grouped product items
Product Name Price Stock Qty
Cilengitide 5mg
$120.00
In stock
Cilengitide 10mg
$180.00
In stock
Cilengitide 25mg
$320.00
In stock
Cilengitide 50mg
$550.00
In stock
Cilengitide 10mM * 1mL in DMSO
$200.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Cilengitide has been cited by 6 publications
  • Marion Bouvet, .et al. , Sci Rep, 2020, 10: 11404 PMID: 32647159
  • Rosalie Richards, .et al. , bioRxiv, 2018, 15 Oct 2018
  • Hiroki Kanazawa, .et al. , PLoS One, 2017, 12(2): e0173051 PMID: 28235037
  • Yasuda J, .et al. , Naunyn Schmiedebergs Arch Pharmacol, 2017, Nov;390(11):1135-1144 PMID: 28785775
  • Yasuda J, .et al. , Eur J Pharmacol, 2017, Jul 15;807:64-70 PMID: 28457922
  • Hsian-Yu Wang, .et al. , Onco Targets Ther, 2016, 9: 2961-2973 PMID: 27284246
  • Biological Activity
    Discription Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.
    Product Information
    Catalog Num A12372
    Formula C27H40N8O7
    Molecular Weight 588.66
    CAS Number 188968-51-6
    SMILES CC(C)[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N1C)CC2=CC=CC=C2)CC(=O)O)CCCN=C(N)N
    Synonyms EMD 12197,EMD-85189,EMD-121974,NSC-707544,D03497
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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