LY2090314

Catalog No.: A12741
GSK-3 inhibitor
LY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) which plays an important role in many pathways, including initiation of protein synthesis, cell proliferation, cell differentiation, and apoptosis.
Grouped product items
Product Name Price Stock Qty
LY2090314 5mg
$100.00
In stock
LY2090314 10mg
$180.00
In stock
LY2090314 25mg
$350.00
In stock
LY2090314 50mg
$550.00
In stock
LY2090314 10mM * 1mL in DMSO
$120.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's LY2090314 has been cited by 1 publications
  • Yuki Shimizu, .et al. , NPJ Precis Oncol, 2022, Mar 17;6(1):16 PMID: 35301419
  • Biological Activity
    Discription LY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) which plays an important role in many pathways, including initiation of protein synthesis, cell proliferation, cell differentiation, and apoptosis.
    Targets
    Target Value
    Product Information
    Catalog Num A12741
    Formula C28H25FN6O3
    Molecular Weight 512.53
    CAS Number 603288-22-8
    SMILES C1CCN(CC1)C(=O)N2CCN3C=C(C4=CC(=CC(=C43)C2)F)C5=C(C(=O)NC5=O)C6=CN=C7N6C=CC=C7
    Synonyms LY 2090314, LY-2090314
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 93 mg/mL (181.45 mM)
    Water Insoluble
    Ethanol Warmed: 2 mg/mL (3.9 mM)
    In vivo 5% DMSO+45% PEG 300+ddH2O 16 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.51 mL 97.56 mL 195.11 mL
    0.5 mM 3.9 mL 19.51 mL 39.02 mL
    1 mM 1.95 mL 9.76 mL 19.51 mL
    5 mM 0.39 mL 1.95 mL 3.9 mL
    Useful Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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