Salubrinal
eIF2α dephosphorylation inhibitor
Important Notice: For research use only. We do not sell to patients.
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eIF2α dephosphorylation inhibitor
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | Salubrinal is a cell-permeable, selective inhibitor of cellular phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF2α). Protects cells from endoplasmic reticulum stress-induced apoptosis (EC50 ~ 15 μM). | ||
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Catalog Num | A12676 |
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Formula | C21H17N4OSCl3 |
Molecular Weight | 479.81 |
CAS Number | 405060-95-9 |
SMILES | C1=CC=C(C=C1)/C=C/C(=O)NC(C(Cl)(Cl)Cl)NC(=S)NC2=CC=CC3=C2N=CC=C3 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 86 mg/mL (179.23 mM) | |
Water | Insoluble | ||
Ethanol | 2 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 20.84 mL | 104.21 mL | 208.42 mL |
0.5 mM | 4.17 mL | 20.84 mL | 41.68 mL |
1 mM | 2.08 mL | 10.42 mL | 20.84 mL |
5 mM | 0.42 mL | 2.08 mL | 4.17 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2