VR23

Catalog No.: A13650
Proteasome inhibitor?€?
VR23 is a small molecule that potently inhibited the activities of trypsin-like proteasomes (IC50 = 1 nM), chymotrypsin-like proteasomes (IC50 = 50-100 nM), and caspase-like proteasomes (IC50 = 3uM).
Grouped product items
Product Name Price Stock Qty
VR23 5mg
$50.00
In stock
VR23 10mg
$90.00
In stock
VR23 25mg
$180.00
In stock
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Biological Activity
Discription VR23 is a small molecule that potently inhibited the activities of trypsin-like proteasomes (IC50 = 1 nM), chymotrypsin-like proteasomes (IC50 = 50-100 nM), and caspase-like proteasomes (IC50 = 3uM).
Targets
Target Value
Product Information
Catalog Num A13650
Formula C19H16ClN5O6S
Molecular Weight 477.88
CAS Number 1624602-30-7
SMILES ClC1=CC2=C(C(N3CCN(S(C4=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C4)(=O)=O)CC3)=CC=N2)C=C1
Synonyms VR-23, VR 23
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO Warmed: 29 mg/mL (60.68 mM)
Water Warmed: 5 mg/mL (10.46 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.93 mL 104.63 mL 209.26 mL
0.5 mM 4.19 mL 20.93 mL 41.85 mL
1 mM 2.09 mL 10.46 mL 20.93 mL
5 mM 0.42 mL 2.09 mL 4.19 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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