Ondansetron (Zofran)

Catalog No.: A11701
Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic (to treat nausea and vomiting). Ondansetron reduces the activity of the vagus nerve, which deactivates the vomiting center in the medulla oblongata, and also blocks serotonin receptors in the chemoreceptor trigger zone.
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Product Name Price Stock Qty
Ondansetron 10mg
$40.00
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Ondansetron 50mg
$60.00
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Ondansetron 100mg
$70.00
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Biological Activity
Discription Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic (to treat nausea and vomiting). Ondansetron reduces the activity of the vagus nerve, which deactivates the vomiting center in the medulla oblongata, and also blocks serotonin receptors in the chemoreceptor trigger zone.
Targets
Target Value
Product Information
Catalog Num A11701
Formula C18H19N3O
Molecular Weight 293.36
CAS Number 99614-02-5
SMILES CC1=NC=CN1CC2CCC3=C(C2=O)C4=CC=CC=C4N3C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 0.09 mg/mL (0.31 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.09 mL 170.44 mL 340.88 mL
0.5 mM 6.82 mL 34.09 mL 68.18 mL
1 mM 3.41 mL 17.04 mL 34.09 mL
5 mM 0.68 mL 3.41 mL 6.82 mL
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