AM251

Catalog No.: A12914
CB1 receptor antagonist
AM251 is a potent CB1 receptor antagonist (IC50 = 8 nM, Ki = 7.49 nM) that displays 306-fold selectivity over CB2 receptors.
Grouped product items
Product Name Price Stock Qty
AM251 10mg
$65.00
In stock
AM251 25mg
$125.00
In stock
AM251 50mg
$240.00
In stock
AM251 100mg
$400.00
In stock
AM251 10mM * 1mL in DMSO
$106.00
In stock
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Biological Activity
Discription AM251 is a potent CB1 receptor antagonist (IC50 = 8 nM, Ki = 7.49 nM) that displays 306-fold selectivity over CB2 receptors.
Targets
Target Value
Product Information
Catalog Num A12914
Formula C22H21Cl2IN4O
Molecular Weight 555.24
CAS Number 183232-66-8
SMILES CC1=C(N(N=C1C(=O)NN2CCCCC2)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)I
Synonyms AM 251, AM-251
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 39 mg/mL (70.24 mM)
Water Insoluble
Ethanol Insoluble
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 7 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.01 mL 90.05 mL 180.1 mL
0.5 mM 3.6 mL 18.01 mL 36.02 mL
1 mM 1.8 mL 9.01 mL 18.01 mL
5 mM 0.36 mL 1.8 mL 3.6 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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