BMS 299897

Catalog No.: A12444
γ-secretase inhibitor
BMS 299897 is an orally active, potent γ-secretase inhibitor (IC50 = 12 nM). Inhibits Aβ40 and Aβ42 formation in vitro (IC50 values are 7.4 and 7.9 nM respectively) and reduces Aβ in the brain, plasma and cerebrospinal fluid in vivo.
Grouped product items
Product Name Stock
BMS 299897 10mg
BMS 299897 25mg
BMS 299897 50mg
BMS 299897 100mg
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Adooq's BMS 299897 has been cited by 1 publications
  • Chao Liu, .et al. , Cell Death Differ, 2018, Apr; 25(4): 661-676 PMID: 29238071
  • Biological Activity
    Discription BMS 299897 is an orally active, potent γ-secretase inhibitor (IC50 = 12 nM). Inhibits Aβ40 and Aβ42 formation in vitro (IC50 values are 7.4 and 7.9 nM respectively) and reduces Aβ in the brain, plasma and cerebrospinal fluid in vivo.
    Product Information
    Catalog Num A12444
    Formula C24H21ClF3NO4S
    Molecular Weight 511.94
    CAS Number 290315-45-6
    SMILES C[C@H](C1=C(C=C(C=C1)F)CCCC(=O)O)N(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl
    Synonyms BMS 299897
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    Keywords: buy BMS 299897 | BMS 299897 Supplier | purchase BMS 299897 | BMS 299897 cost | BMS 299897 manufacturer | order BMS 299897 | BMS 299897 distributor | buy 290315-45-6 | 290315-45-6 Supplier | purchase 290315-45-6 | 290315-45-6 cost | 290315-45-6 manufacturer | order 290315-45-6 | 290315-45-6 distributor