Cilengitide trifluoroacetate

Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.
Grouped product items
Product Name Price Stock Qty
Cilengitide trifluoroacetate 5mg
$150.00
In stock
Cilengitide trifluoroacetate 10mg
$200.00
In stock
Cilengitide trifluoroacetate 25mg
$350.00
In stock
Cilengitide trifluoroacetate 50mg
$600.00
In stock
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Adooq Products cited in reputable paper
Adooq's Cilengitide trifluoroacetate has been cited by 1 publications
  • Yi Han Tan, .et al. , Cell Microbiol, 2017, Aug;19(8) PMID: 28186697
  • Biological Activity
    Discription Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.
    Targets
    Target Value
    Product Information
    Catalog Num A12371
    Formula C29H41N8O9F3
    Molecular Weight 702.7
    CAS Number 199807-35-7
    SMILES CC(C)[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N1C)Cc2ccccc2)CC(=O)O)CCCNC(=N)N.C(=O)(C(F)(F)F)O
    Synonyms EMD 12197,EMD-85189,EMD-121974,NSC-707544,D03497
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 89 mg/mL (126.66 mM)
    Water 7 mg/mL (9.96 mM)
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 14.23 mL 71.15 mL 142.31 mL
    0.5 mM 2.85 mL 14.23 mL 28.46 mL
    1 mM 1.42 mL 7.12 mL 14.23 mL
    5 mM 0.28 mL 1.42 mL 2.85 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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