AMG-073 HCl (Cinacalcet HCl)
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | AMG-073 HCl (Cinacalcet HCl) represents a new class of compounds for the treatment of hyperparathyroidism known as calcimimetics, which reduce parathyroid hormone (PTH) synthesis and secretion by increasing the sensitivity of the parathyroid calcium-sensing receptor (CaR) to extracellular calcium. | ||
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Catalog Num | A10219 |
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Formula | C22H23ClF3N |
Molecular Weight | 393.9 |
CAS Number | 364782-34-3 |
SMILES | C[C@H](C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl |
Synonyms | Mimpara, Sensipar |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 67 mg/mL (170.1 mM) | |
Water | Insoluble | ||
Ethanol | 28 mg/mL (71.09 mM) | ||
In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 25.39 mL | 126.94 mL | 253.87 mL |
0.5 mM | 5.08 mL | 25.39 mL | 50.77 mL |
1 mM | 2.54 mL | 12.69 mL | 25.39 mL |
5 mM | 0.51 mL | 2.54 mL | 5.08 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2