Naftopidil 2HCl

Catalog No.: A10619
5-HT1A and α1-adrenergic receptor antagonist
Naftopidil 2HCl is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.
Grouped product items
Product Name Price Stock Qty
Naftopidil Dihydrochloride 25mg
$35.00
In stock
Naftopidil Dihydrochloride 50mg
$50.00
In stock
Naftopidil Dihydrochloride 100mg
$90.00
In stock
Naftopidil Dihydrochloride 500mg
$330.00
In stock
Naftopidil 2HCl 10mM * 1mL in DMSO
$66.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Naftopidil 2HCl is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.
Targets
Target Value
Product Information
Catalog Num A10619
Formula C24H28N2O3.2HCl
Molecular Weight 465.4
CAS Number 57149-08-3
SMILES COC1=CC=CC=C1N2CCN(CC2)CC(COC3=CC=CC4=CC=CC=C43)O.Cl.Cl
Synonyms Flivas, KT-611, Avishot
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 35 mg/mL (75.2 mM)
Water Insoluble
Ethanol 2 mg/mL (4.29 mM)
In vivo 0.5% CMC 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.49 mL 107.43 mL 214.87 mL
0.5 mM 4.3 mL 21.49 mL 42.97 mL
1 mM 2.15 mL 10.74 mL 21.49 mL
5 mM 0.43 mL 2.15 mL 4.3 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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