NQDI 1

Catalog No.: A12838
ASK1 inhibitor
NQDI 1 is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50 = 3 μM, Ki = 500 nM).
Grouped product items
Product Name Price Stock Qty
NQDI 1 10mg
$80.00
In stock
NQDI 1 25mg
$150.00
In stock
NQDI 1 50mg
$220.00
In stock
NQDI 1 100mg
$350.00
In stock
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Biological Activity
Discription NQDI 1 is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50 = 3 μM, Ki = 500 nM).
Targets
Target Value
Product Information
Catalog Num A12838
Formula C19H13NO4
Molecular Weight 319.31
CAS Number 175026-96-7
SMILES O=C1NC2=CC=CC3=C2C(C4=CC=CC=C4C3=O)=C1C(OCC)=O
Synonyms NQDI-1, NQDI1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 20 mg/mL (62.63 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5%dmso+40%PEG300+5%tween-80+ddH2O 0.4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.32 mL 156.59 mL 313.18 mL
0.5 mM 6.26 mL 31.32 mL 62.64 mL
1 mM 3.13 mL 15.66 mL 31.32 mL
5 mM 0.63 mL 3.13 mL 6.26 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

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This equation is commonly abbreviated as: C1V1 = C2V2

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