Pemetrexed disodium (Alimta)
DHFR inhibitor
Important Notice: For research use only. We do not sell to patients.
Other Forms of Pemetrexed disodium (Alimta)
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DHFR inhibitor
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | Pemetrexed disodium is chemically similar to folic acid and is in the class of chemotherapy drugs called folate antimetabolites. It works by inhibiting three enzymes used in purine and pyrimidine synthesis?€?thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase. | ||
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Catalog Num | A10707 |
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Formula | C20H19N5Na2O6 |
Molecular Weight | 471.4 |
CAS Number | 150399-23-8 |
SMILES | C1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Na+].[Na+] |
Synonyms | LY-231514 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | Insoluble | |
Water | 87 mg/mL (184.56 mM) | ||
Ethanol | Insoluble | ||
In vivo | Saline | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 21.21 mL | 106.07 mL | 212.13 mL |
0.5 mM | 4.24 mL | 21.21 mL | 42.43 mL |
1 mM | 2.12 mL | 10.61 mL | 21.21 mL |
5 mM | 0.42 mL | 2.12 mL | 4.24 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2