CGI1746

Catalog No.: A11348
BTK inhibitor
CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation.
Grouped product items
Product Name Price Stock Qty
CGI1746 5mg
$65.00
In stock
CGI1746 10mg
$100.00
In stock
CGI1746 25mg
$180.00
In stock
CGI1746 10mM * 1mL in DMSO
$110.00
In stock
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Biological Activity
Discription CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation.
Targets
Target Value
Product Information
Catalog Num A11348
Formula C34H37N5O4
Molecular Weight 579.7
CAS Number 910232-84-7
SMILES CC1=C(C=CC=C1NC(=O)C2=CC=C(C=C2)C(C)(C)C)C3=CN(C(=O)C(=N3)NC4=CC=C(C=C4)C(=O)N5CCOCC5)C
Synonyms CGI 1746, CGI-1746
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 91 mg/mL (156.98 mM)
Water Insoluble
Ethanol Warmed: 30 mg/mL (51.75 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.25 mL 86.25 mL 172.5 mL
0.5 mM 3.45 mL 17.25 mL 34.5 mL
1 mM 1.73 mL 8.63 mL 17.25 mL
5 mM 0.35 mL 1.73 mL 3.45 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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