Combretastatin A4

Catalog No.: A12601
Combretastatin A4 is an antitumor, antiangiogenic and antimetastatic agent, in vitro and in vivo. Combretastatin A4 is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM.
Grouped product items
Product Name Price Stock Qty
Combretastatin A4 10mg
$70.00
In stock
Combretastatin A4 25mg
$140.00
In stock
Combretastatin A4 50mg
$220.00
In stock
Combretastatin A4 100mg
$380.00
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Biological Activity
Discription Combretastatin A4 is an antitumor, antiangiogenic and antimetastatic agent, in vitro and in vivo. Combretastatin A4 is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM.
Product Information
Catalog Num A12601
Formula C18H20O5
Molecular Weight 316.35
CAS Number 117048-59-6
SMILES COC1=C(C=C(C=C1)/C=C\C2=CC(=C(C(=C2)OC)OC)OC)O
Synonyms CRC 87-09, NSC 817373
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 58 mg/mL (183.34 mM)
Water Insoluble
Ethanol Warmed: 31 mg/mL (97.99 mM)
In vivo 5% DMSO+50% PEG 300+ddH2O 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.61 mL 158.05 mL 316.11 mL
0.5 mM 6.32 mL 31.61 mL 63.22 mL
1 mM 3.16 mL 15.81 mL 31.61 mL
5 mM 0.63 mL 3.16 mL 6.32 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

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This equation is commonly abbreviated as: C1V1 = C2V2

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