GNE 9605
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | GNE-9605 is a highly potent and selective leucine-rich repeat kinase 2 (LRRK2) inhibitor with Ki and IC50 of 2 nM and 19 nM, respectively. | ||
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Targets |
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Catalog Num | A14149 |
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Formula | C17H20ClF4N7O |
Molecular Weight | 449.83 |
CAS Number | 1536200-31-3 |
SMILES | CNC1=NC(=NC=C1C(F)(F)F)NC2=C(N(N=C2)[C@H]3CCN(C[C@@H]3F)C4COC4)Cl |
Synonyms | GNE-9605,GNE9605 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 84 mg/mL (186.73 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 11 mg/mL (24.45 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 22.23 mL | 111.15 mL | 222.31 mL |
0.5 mM | 4.45 mL | 22.23 mL | 44.46 mL |
1 mM | 2.22 mL | 11.12 mL | 22.23 mL |
5 mM | 0.44 mL | 2.22 mL | 4.45 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2