KC7F2

Catalog No.: A15359
HIF inhibitor
KC7F2 is an inhibitor of HIF-1α protein translation, but not transcription, that suppresses phosphorylation of two key regulators of protein synthesis, eukaryotic translation initiation factor 4E binding protein 1 (4EBP1) and p70 S6 kinase (S6K).
Grouped product items
Product Name Price Stock Qty
KC7F2 10mg
$55.00
In stock
KC7F2 50mg
$190.00
In stock
KC7F2 100mg
$280.00
In stock
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Biological Activity
Discription KC7F2 is an inhibitor of HIF-1α protein translation, but not transcription, that suppresses phosphorylation of two key regulators of protein synthesis, eukaryotic translation initiation factor 4E binding protein 1 (4EBP1) and p70 S6 kinase (S6K).
Targets
Target Value
Product Information
Catalog Num A15359
Formula C16H16Cl4N2O4S4
Molecular Weight 570.38
CAS Number 927822-86-4
SMILES C1=CC(=C(C=C1Cl)S(=O)(=O)NCCSSCCNS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl)Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 94 mg/mL (164.8 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.53 mL 87.66 mL 175.32 mL
0.5 mM 3.51 mL 17.53 mL 35.06 mL
1 mM 1.75 mL 8.77 mL 17.53 mL
5 mM 0.35 mL 1.75 mL 3.51 mL
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