RO4929097
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | RO4929097 is an orally bioavailable, small-molecule gamma secretase (GS) inhibitor with an IC50 of 4 nM. | ||
---|---|---|---|
Targets |
|
Catalog Num | A10802 |
---|---|
Formula | C22H20F5N3O3 |
Molecular Weight | 469.4 |
CAS Number | 847925-91-1 |
SMILES | CC(C)(C(=O)NCC(C(F)(F)F)(F)F)C(=O)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3NC1=O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 92 mg/mL (195.99 mM) | |
Water | Insoluble | ||
Ethanol | 16 mg/mL | ||
In vivo | 2% DMSO+30% PEG 300+5% Tween+ddH2O | 9 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.3 mL | 106.52 mL | 213.04 mL |
0.5 mM | 4.26 mL | 21.3 mL | 42.61 mL |
1 mM | 2.13 mL | 10.65 mL | 21.3 mL |
5 mM | 0.43 mL | 2.13 mL | 4.26 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2