TH588

Catalog No.: A15537
MTH1 inhibitor
TH588 is first-in-class nudix hydrolase family inhibitor that potently and selectively engage and inhibit the MTH1(IC50= 5 nM) in cells,
Grouped product items
Product Name Price Stock Qty
TH588 10mg
$100.00
In stock
TH588 25mg
$140.00
In stock
TH588 50mg
$240.00
In stock
Bulk Size
Bulk Discount
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription TH588 is first-in-class nudix hydrolase family inhibitor that potently and selectively engage and inhibit the MTH1(IC50= 5 nM) in cells,
Targets
Target Value
Product Information
Catalog Num A15537
Formula C13H12Cl2N4
Molecular Weight 295.17
CAS Number 1609960-31-7
SMILES C1CC1NC2=NC(=NC(=C2)C3=C(C(=CC=C3)Cl)Cl)N
Synonyms TH-588, TH 588
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO Warmed: 19 mg/mL (64.36 mM)
Water Insoluble
Ethanol Warmed: 1 mg/mL (3.38 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.88 mL 169.39 mL 338.79 mL
0.5 mM 6.78 mL 33.88 mL 67.76 mL
1 mM 3.39 mL 16.94 mL 33.88 mL
5 mM 0.68 mL 3.39 mL 6.78 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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