AZD5363

Catalog No.: A11759
AKT inhibitor
AZD5363 is a potent inhibitor of AKT with pharmacodynamic activity in vivo, has potential to treat a range of solid and hematologic tumors as monotherapy or a combinatorial agent.
Grouped product items
Product Name Price Stock Qty
AZD5363 5mg
$70.00
In stock
AZD5363 10mg
$120.00
In stock
AZD5363 25mg
$200.00
In stock
AZD5363 50mg
$300.00
In stock
AZD5363 10mM * 1mL in DMSO
$85.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's AZD5363 has been cited by 4 publications
  • Hiroyuki Tsuchiya, .et al. , Curr Issues Mol Biol, 2023, Jan 29;45(2):1073-1085 PMID: 36826016
  • Giri R. Gnawali, .et al. , Medicinal Chemistry Research, 2022, 31: 1154-1175
  • Jeremiah J Bearss, .et al. , EMBO Rep, 2021, Apr 7;22(4):e50835 PMID: 33586867
  • Jin H. Song, .et al. , Mol Cancer Ther, 2018, Dec;17(12):2710-2721 PMID: 30190422
  • Biological Activity
    Discription AZD5363 is a potent inhibitor of AKT with pharmacodynamic activity in vivo, has potential to treat a range of solid and hematologic tumors as monotherapy or a combinatorial agent.
    Targets
    Target Value
    Product Information
    Catalog Num A11759
    Formula C21H25ClN6O2
    Molecular Weight 428.9
    CAS Number 1143532-39-1
    SMILES C1CN(CCC1(C(=O)N[C@@H](CCO)C2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4
    Synonyms AZD 5363, AZD-5363
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 79 mg/mL (184.18 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.32 mL 116.58 mL 233.15 mL
    0.5 mM 4.66 mL 23.32 mL 46.63 mL
    1 mM 2.33 mL 11.66 mL 23.32 mL
    5 mM 0.47 mL 2.33 mL 4.66 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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