IU1

Catalog No.: A13209
Usp14 inhibitor
IU1 is a selective inhibitor of Usp14. It inhibits the catalytic activity of proteasome-associated Usp14 in vitro (IC50 < 4 uM).
Grouped product items
Product Name Price Stock Qty
IU1 25mg
$100.00
In stock
IU1 50mg
$180.00
In stock
IU1 100mg
$300.00
In stock
IU1 10mM * 1mL in DMSO
$71.00
In stock
Bulk Size
Bulk Discount
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's IU1 has been cited by 2 publications
  • Kevin Bohm, .et al. , Arch Pharm (Weinheim), 2023, Jul;356(7):e2200661 PMID: 37196427
  • Anurag Rathore, .et al. , Sci Rep, 2020, 10: 5350 PMID: 32210344
  • Biological Activity
    Discription IU1 is a selective inhibitor of Usp14. It inhibits the catalytic activity of proteasome-associated Usp14 in vitro (IC50 < 4 uM).
    Targets
    Target Value
    Product Information
    Catalog Num A13209
    Formula C18H21FN2O
    Molecular Weight 300.37
    CAS Number 314245-33-5
    SMILES CC1=CC(=C(N1C2=CC=C(C=C2)F)C)C(=O)CN3CCCC3
    Synonyms IU-1
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 51 mg/mL (169.79 mM)
    Water Insoluble
    Ethanol 51 mg/mL (169.79 mM)
    In vivo 2% DMSO+30% PEG 300+2% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 33.29 mL 166.46 mL 332.92 mL
    0.5 mM 6.66 mL 33.29 mL 66.58 mL
    1 mM 3.33 mL 16.65 mL 33.29 mL
    5 mM 0.67 mL 3.33 mL 6.66 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

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