MI-773

Catalog No.: A15440
MDM2 inhibitor
MI-773 is an orally available MDM2 antagonist with Ki of 0.88 nM.
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Product Name Stock
MI-773 5mg
MI-773 10mg
MI-773 25mg
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Biological Activity
Discription MI-773 is an orally available MDM2 antagonist with Ki of 0.88 nM.
Targets
Target Value
Product Information
Catalog Num A15440
Formula C29H34Cl2FN3O3
Molecular Weight 562.5
CAS Number 1303607-60-4
SMILES CC(C)(C)C[C@H]1[C@@]2([C@H]([C@@H](N1)C(=O)NC3CCC(CC3)O)C4=C(C(=CC=C4)Cl)F)C5=C(C=C(C=C5)Cl)NC2=O
Synonyms SAR405838,MI 773, MI773
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 93 mg/mL (165.33 mM)
Water Insoluble
Ethanol Warmed: 29 mg/mL (51.55 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.78 mL 88.89 mL 177.78 mL
0.5 mM 3.56 mL 17.78 mL 35.56 mL
1 mM 1.78 mL 8.89 mL 17.78 mL
5 mM 0.36 mL 1.78 mL 3.56 mL
Useful Calculator

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