ACTB-1003

Catalog No.: A14431
FGFR1 inhibitor
ACTB-1003 is an oral kinase inhibitor targeting cancer mutations (FGFR inhibition), angiogenesis (inhibition of VEGFR2 and Tie-2) and induces apoptosis (targeting RSK and p70S6K, downstream of PI3 kinase).
Grouped product items
Product Name Price Stock Qty
ACTB-1003 5mg
$120.00
In stock
ACTB-1003 10mg
$200.00
In stock
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Biological Activity
Discription ACTB-1003 is an oral kinase inhibitor targeting cancer mutations (FGFR inhibition), angiogenesis (inhibition of VEGFR2 and Tie-2) and induces apoptosis (targeting RSK and p70S6K, downstream of PI3 kinase).
Targets
Target Value
Product Information
Catalog Num A14431
Formula C27H26F5N7O3
Molecular Weight 591.53
CAS Number 939805-30-8
SMILES COCC1=C(N2C(=C1C3=CC(=C(C=C3)NC(=O)NC4=C(C=CC(=C4)C(F)(F)F)F)F)C(=NC=N2)N)CN5CCOCC5
Synonyms ACTB1003, ACTB 1003
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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