EMD-1214063

Catalog No.: A11257
c-Met Inhibitor
EMD-1214063 is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. It binds to MET tyrosine kinase and disrupts MET signal transduction pathways, which may induce apoptosis in tumor cells overexpressing this kinase.
Grouped product items
Product Name Price Stock Qty
EMD-1214063 5mg
$110.00
In stock
EMD-1214063 10mg
$200.00
In stock
EMD-1214063 50mg
$400.00
In stock
EMD-1214063 100mg
$700.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription EMD-1214063 is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. It binds to MET tyrosine kinase and disrupts MET signal transduction pathways, which may induce apoptosis in tumor cells overexpressing this kinase.
Targets
Target Value
Product Information
Catalog Num A11257
Formula C29H28N6O2
Molecular Weight 492.6
CAS Number 1100598-32-0
SMILES CN1CCC(CC1)COC2=CN=C(N=C2)C3=CC(=CC=C3)CN4C(=O)C=CC(=N4)C5=CC=CC(=C5)C#N
Synonyms EMD1214063
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO Warmed: 4 mg/mL (8.12 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+corn oil 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.3 mL 101.5 mL 203 mL
0.5 mM 4.06 mL 20.3 mL 40.6 mL
1 mM 2.03 mL 10.15 mL 20.3 mL
5 mM 0.41 mL 2.03 mL 4.06 mL
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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