Rofecoxib (Vioxx)

Catalog No.: A11918
COX-2 inhibitor
Rofecoxib (Vioxx) is a COX-2 inhibitor with IC50 of 18 nM.
Grouped product items
Product Name Price Stock Qty
Rofecoxib (Vioxx) 250mg
$80.00
In stock
Rofecoxib (Vioxx) 500mg
$150.00
In stock
Rofecoxib (Vioxx) 1000mg
$250.00
In stock
Rofecoxib (Vioxx) 2000mg
$400.00
In stock
Rofecoxib (Vioxx) 10mM * 1mL in DMSO
$60.00
In stock
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Biological Activity
Discription Rofecoxib (Vioxx) is a COX-2 inhibitor with IC50 of 18 nM.
Targets
Target Value
Product Information
Catalog Num A11918
Formula C17H14O4S
Molecular Weight 314.35
CAS Number 162011-90-7
SMILES CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=CC=C3
Synonyms Vioxx
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 62 mg/mL (197.22 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.81 mL 159.06 mL 318.12 mL
0.5 mM 6.36 mL 31.81 mL 63.62 mL
1 mM 3.18 mL 15.91 mL 31.81 mL
5 mM 0.64 mL 3.18 mL 6.36 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

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