TG101209

Catalog No.: A11180
JAK2 inhibitor

TG101209, a novel JAK2 inhibitor, has significant in vitro activity in multiple myeloma and displays preferential cytotoxicity for CD45+ myeloma cells.

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Product Name Price Stock Qty
TG101209 5mg
$70.00
In stock
TG101209 10mg
$120.00
In stock
TG101209 50mg
$270.00
In stock
TG101209 100mg
$485.00
In stock
TG101209 10mM * 1mL in DMSO
$100.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription

TG101209, a novel JAK2 inhibitor, has significant in vitro activity in multiple myeloma and displays preferential cytotoxicity for CD45+ myeloma cells.

Targets
Target Value
Product Information
Catalog Num A11180
Formula C26H35N7O2S
Molecular Weight 509.67
CAS Number 936091-14-4
SMILES CN1CCN(CC1)C2=CC=C(C=C2)NC3N=C(NC4=CC(=CC=C4)S(=O)(=O)NC(C)(C)C)C(C)=CN=3
Synonyms TG-101209
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 94 mg/mL (184.42 mM)
Water Insoluble
Ethanol Insoluble
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 11 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.62 mL 98.1 mL 196.21 mL
0.5 mM 3.92 mL 19.62 mL 39.24 mL
1 mM 1.96 mL 9.81 mL 19.62 mL
5 mM 0.39 mL 1.96 mL 3.92 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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