JANEX-1

Catalog No.: A15134
JAK3 inhibitor
Janex-1 is a cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3 (IC50 = 78 uM); has no effect on JAK1, JAK2, or Zap/Syk or SRC tyrosine kinases.
Grouped product items
Product Name Price Stock Qty
JANEX-1 5mg
$95.00
In stock
JANEX-1 10mg
$165.00
In stock
JANEX-1 25mg
$375.00
In stock
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Bulk Discount
Free Delivery on orders over $500

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Biological Activity
Discription Janex-1 is a cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3 (IC50 = 78 uM); has no effect on JAK1, JAK2, or Zap/Syk or SRC tyrosine kinases.
Targets
Target Value
Product Information
Catalog Num A15134
Formula C16H15N3O3
Molecular Weight 297.31
CAS Number 202475-60-3
SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)O)OC
Synonyms WHI-P131, Janex 1, WHI-P 131
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 5 mg/mL (16.81 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.63 mL 168.17 mL 336.35 mL
0.5 mM 6.73 mL 33.63 mL 67.27 mL
1 mM 3.36 mL 16.82 mL 33.63 mL
5 mM 0.67 mL 3.36 mL 6.73 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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