Ketoconazole

Catalog No.: A10498
P450 inhibitor
As an antifungal, ketoconazole is structurally similar to imidazole, and interferes with the fungal synthesis of ergosterol, a constituent of fungal cell membranes, as well as certain enzymes.
Grouped product items
Product Name Price Stock Qty
Ketoconazole 100mg
$50.00
In stock
Ketoconazole 200mg
$85.00
In stock
Ketoconazole 500mg
$150.00
In stock
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Biological Activity
Discription As an antifungal, ketoconazole is structurally similar to imidazole, and interferes with the fungal synthesis of ergosterol, a constituent of fungal cell membranes, as well as certain enzymes.
Targets
Target Value
Product Information
Catalog Num A10498
Formula C26H28Cl2N4O4
Molecular Weight 531.4
CAS Number 65277-42-1
SMILES CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OC[C@H]3CO[C@](O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
Synonyms Nizoral, Extina, Xolegel, Kuric
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO Warmed: 5 mg/mL (9.4 mM)
Water Insoluble
Ethanol 7 mg/mL
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.82 mL 94.09 mL 188.18 mL
0.5 mM 3.76 mL 18.82 mL 37.64 mL
1 mM 1.88 mL 9.41 mL 18.82 mL
5 mM 0.38 mL 1.88 mL 3.76 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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