Pemetrexed disodium (Alimta)

Pemetrexed disodium is chemically similar to folic acid and is in the class of chemotherapy drugs called folate antimetabolites. It works by inhibiting three enzymes used in purine and pyrimidine synthesis?€?thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase.
Grouped product items
Product Name Price Stock Qty
Pemetrexed disodium 10mg
$40.00
In stock
Pemetrexed disodium 50mg
$55.00
In stock
Pemetrexed disodium 100mg
$80.00
In stock
Pemetrexed disodium 200mg
$130.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Pemetrexed disodium (Alimta) has been cited by 1 publications
  • Adi Jacob Berger, .et al. , Nat Cancer, 2021, 2, 1055-1070 PMID: 35121883
  • Biological Activity
    Discription Pemetrexed disodium is chemically similar to folic acid and is in the class of chemotherapy drugs called folate antimetabolites. It works by inhibiting three enzymes used in purine and pyrimidine synthesis?€?thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase.
    Targets
    Target Value
    Product Information
    Catalog Num A10707
    Formula C20H19N5Na2O6
    Molecular Weight 471.4
    CAS Number 150399-23-8
    SMILES C1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]
    Synonyms LY-231514
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Insoluble
    Water 87 mg/mL (184.56 mM)
    Ethanol Insoluble
    In vivo Saline 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.21 mL 106.07 mL 212.13 mL
    0.5 mM 4.24 mL 21.21 mL 42.43 mL
    1 mM 2.12 mL 10.61 mL 21.21 mL
    5 mM 0.42 mL 2.12 mL 4.24 mL
    Useful Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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