SIS3
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | SIS3 is a novel specific inhibitor of Smad3. It has effect on transforming growth factor-beta1-induced extracellular matrix expression. | ||
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Targets |
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Catalog Num | A16065 |
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Formula | C28H27N3O3.HCl |
Molecular Weight | 489.99 |
CAS Number | 521984-48-5 |
SMILES | CN1C(C2=CC=CC=C2)=C(C3=C1N=CC=C3)/C([H])=C([H])/C(N4CCC5=CC(OC)=C(OC)C=C5C4)=O.Cl |
Synonyms | SIS 3 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 92 mg/mL (187.76 mM) | |
Water | Insoluble | ||
Ethanol | 23 mg/mL (46.94 mM) | ||
In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 20.41 mL | 102.04 mL | 204.09 mL |
0.5 mM | 4.08 mL | 20.41 mL | 40.82 mL |
1 mM | 2.04 mL | 10.2 mL | 20.41 mL |
5 mM | 0.41 mL | 2.04 mL | 4.08 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2