P 22077

Catalog No.: A12933
USP7 inhibitor
P 22077 is a cell-permeable inhibitor of the ubiquitin-specific protease (IC?? = 8.6 μM) and the closely related deubiquitinase (DUB) USP47.
Grouped product items
Product Name Price Stock Qty
P 22077 10mg
$70.00
In stock
P 22077 25mg
$140.00
In stock
P 22077 50mg
$220.00
In stock
P 22077 100mg
$380.00
In stock
P 22077 10mM * 1mL in DMSO
$97.00
In stock
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Biological Activity
Discription P 22077 is a cell-permeable inhibitor of the ubiquitin-specific protease (IC?? = 8.6 μM) and the closely related deubiquitinase (DUB) USP47.
Targets
Target Value
Product Information
Catalog Num A12933
Formula C12H7F2NO3S2
Molecular Weight 315.32
CAS Number 1247819-59-5
SMILES CC(=O)C1=CC(=C(S1)SC2=C(C=C(C=C2)F)F)[N+](=O)[O-]
Synonyms P22077
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 57 mg/mL (180.76 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+30% PEG 300+2% Tween 80+ddH2O 2 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.71 mL 158.57 mL 317.14 mL
0.5 mM 6.34 mL 31.71 mL 63.43 mL
1 mM 3.17 mL 15.86 mL 31.71 mL
5 mM 0.63 mL 3.17 mL 6.34 mL
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