PF-03084014

Catalog No.: A11259
γ-secretase inhibitor
PF-03084014 is a reversible and selective inhibitor of γ-secretase with IC50 value of 6.2 nM .
Grouped product items
Product Name Price Stock Qty
PF-03084014 5mg
$105.00
In stock
PF-03084014 10mg
$179.00
In stock
PF-03084014 25mg
$315.00
In stock
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Biological Activity
Discription PF-03084014 is a reversible and selective inhibitor of γ-secretase with IC50 value of 6.2 nM .
Product Information
Catalog Num A11259
Formula C27H41F2N5O
Molecular Weight 489.64
CAS Number 865773-15-5, 1290543-63-3
SMILES CCC[C@@H](C(=O)NC1=CN(C=N1)C(C)(C)CNCC(C)(C)C)N[C@H]2CCC3=CC(=CC(=C3C2)F)F
Synonyms PF 03084014, PF03084014
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO Warmed: 89 mg/mL (181.76 mM)
Water Insoluble
Ethanol Warmed: 89 mg/mL (181.76 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.42 mL 102.12 mL 204.23 mL
0.5 mM 4.08 mL 20.42 mL 40.85 mL
1 mM 2.04 mL 10.21 mL 20.42 mL
5 mM 0.41 mL 2.04 mL 4.08 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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