SBI-0206965

Catalog No.: A15795
ULK1 inhibitor
SBI-0206965 is a potent, selective and cell permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for the highly related kinase ULK2 .
Grouped product items
Product Name Price Stock Qty
SBI-0206965 5mg
$65.00
In stock
SBI-0206965 10mg
$120.00
In stock
SBI-0206965 25mg
$220.00
In stock
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Adooq Products cited in reputable paper
Adooq's SBI-0206965 has been cited by 2 publications
  • SR Bonam, .et al. , Cells, 2020, May; 9(5): 1321 PMID: 32466347
  • Altea Rocchi, .et al. , PLoS Genet, 2017, Aug; 13(8): e1006962 PMID: 28806762
  • Biological Activity
    Discription SBI-0206965 is a potent, selective and cell permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for the highly related kinase ULK2 .
    Targets
    Target Value
    Product Information
    Catalog Num A15795
    Formula C21H21BrN4O5
    Molecular Weight 489.32
    CAS Number 1884220-36-3
    SMILES CNC(=O)C1=CC=CC=C1OC2=NC(=NC=C2Br)NC3=CC(=C(C(=C3)OC)OC)OC
    Synonyms SBI 0206965, SBI0206965
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 90 mg/mL (183.92 mM)
    Water Insoluble
    Ethanol Warmed: 9 mg/mL (18.39 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 20.44 mL 102.18 mL 204.37 mL
    0.5 mM 4.09 mL 20.44 mL 40.87 mL
    1 mM 2.04 mL 10.22 mL 20.44 mL
    5 mM 0.41 mL 2.04 mL 4.09 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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