Combretastatin A4
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Combretastatin A4 is an antitumor, antiangiogenic and antimetastatic agent, in vitro and in vivo. Combretastatin A4 is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM. |
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Catalog Num | A12601 |
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Formula | C18H20O5 |
Molecular Weight | 316.35 |
CAS Number | 117048-59-6 |
SMILES | COC1=C(C=C(C=C1)/C=C\C2=CC(=C(C(=C2)OC)OC)OC)O |
Synonyms | CRC 87-09, NSC 817373 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 58 mg/mL (183.34 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 31 mg/mL (97.99 mM) | ||
In vivo | 5% DMSO+50% PEG 300+ddH2O | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 31.61 mL | 158.05 mL | 316.11 mL |
0.5 mM | 6.32 mL | 31.61 mL | 63.22 mL |
1 mM | 3.16 mL | 15.81 mL | 31.61 mL |
5 mM | 0.63 mL | 3.16 mL | 6.32 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2