TNP-470

Catalog No.: A14014
MetAP-2 inhibitor
TNP 470 is an analog of Fumagillin that displays potent antiangiogenic activity in vitro. Shown to inhibit MetAP-2 (methionine aminopeptidase type II ).
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Product Name Stock
TNP-470 10mg
TNP-470 25mg
TNP-470 50mg
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Biological Activity
Discription TNP 470 is an analog of Fumagillin that displays potent antiangiogenic activity in vitro. Shown to inhibit MetAP-2 (methionine aminopeptidase type II ).
Product Information
Catalog Num A14014
Formula C19H28CINO6
Molecular Weight 401.88
CAS Number 129298-91-5
SMILES CC(=CC[C@H]1[C@](O1)(C)C2[C@@H]([C@@H](CC[C@]23CO3)OC(=O)NC(=O)CCl)OC)C
Synonyms TNP470, TNP 470, O-(Chloroacetyl-carbamoyl) Fumagillol, NSC 642492, AGM-1470
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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