Dubermatinib (TP-0903)

Catalog No.: A15776
AXL Inhibitor
TP-0903 is a potent and selective Axl kinase inhibitor with IC50 of 27 nM.
Grouped product items
Product Name Price Stock Qty
TP-0903 5mg
$65.00
In stock
TP-0903 10mg
$90.00
In stock
TP-0903 25mg
$160.00
In stock
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Biological Activity
Discription TP-0903 is a potent and selective Axl kinase inhibitor with IC50 of 27 nM.
Targets
Target Value
Product Information
Catalog Num A15776
Formula C24H30ClN7O2S
Molecular Weight 516.06
CAS Number 1341200-45-0
SMILES CN1CCN(CC1)CC2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=CC=C4S(=O)(=O)N(C)C)Cl
Synonyms TP0903, TP 0903
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO Warmed: 3 mg/mL (5.81 mM)
Water Insoluble
Ethanol Warmed: 1 mg/mL (1.93 mM)
In vivo 0.5% CMC Na+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.38 mL 96.89 mL 193.78 mL
0.5 mM 3.88 mL 19.38 mL 38.76 mL
1 mM 1.94 mL 9.69 mL 19.38 mL
5 mM 0.39 mL 1.94 mL 3.88 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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