NVP-BKM120 Hydrochloride (Buparlisib HCl)

Catalog No.: A15195

PI3K Inhibitor

NVP-BKM120 Hydrochloride is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM, respectively. Reduced potency against VPS34, mTOR, DNA-PK, with little activity to PI4Kβ.
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Product Name Price Stock Qty
NVP-BKM120 Hydrochloride 5mg
$60.00
In stock
NVP-BKM120 Hydrochloride 10mg
$90.00
In stock
NVP-BKM120 Hydrochloride 50mg
$150.00
In stock
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Biological Activity
Discription NVP-BKM120 Hydrochloride is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM, respectively. Reduced potency against VPS34, mTOR, DNA-PK, with little activity to PI4Kβ.
Targets
Target Value
Product Information
Catalog Num A15195
Formula C18H21F3N6O2.HCl
Molecular Weight 446.85
CAS Number 1312445-63-8
SMILES C1COCCN1C2=NC(=NC(=C2)C3=CN=C(C=C3C(F)(F)F)N)N4CCOCC4.Cl
Synonyms BKM-120 hydrochloride, BKM120 hydrochloride, BKM 120 hydrochloride
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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