NMS-1286937
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | NMS-1286937 is an orally bioavailable, small-molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. | ||
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Targets |
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Catalog Num | A13045 |
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Formula | C24H27F3N8O3 |
Molecular Weight | 532.52 |
CAS Number | 1034616-18-6 |
SMILES | CN1CCN(CC1)C2=CC(=C(C=C2)OC(F)(F)F)NC3=NC=C4CCC5=C(C4=N3)N(N=C5C(=O)N)CCO |
Synonyms | NMS1286937, NMS-P937 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Warmed: 38 mg/mL (71.36 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 9 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 18.78 mL | 93.89 mL | 187.79 mL |
0.5 mM | 3.76 mL | 18.78 mL | 37.56 mL |
1 mM | 1.88 mL | 9.39 mL | 18.78 mL |
5 mM | 0.38 mL | 1.88 mL | 3.76 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2