A-1331852

Catalog No.: A16190
BCL-XL inhibitor
A-1331852 is a potent and selective BCL-XL inhibitor. BCL-XL is the major antiapoptotic survival protein and may be a novel therapeutic target in CML.
Grouped product items
Product Name Price Stock Qty
A-1331852 5mg
$120.00
In stock
A-1331852 10mg
$200.00
In stock
A-1331852 50mg
$670.00
In stock
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Biological Activity
Discription A-1331852 is a potent and selective BCL-XL inhibitor. BCL-XL is the major antiapoptotic survival protein and may be a novel therapeutic target in CML.
Targets
Target Value
Product Information
Catalog Num A16190
Formula C38H38N6O3S
Molecular Weight 658.82
CAS Number 1430844-80-6
SMILES CC1=C(C=NN1CC23CC4CC(C2)CC(C4)C3)C5=C(N=C(C=C5)N6CCC7=CC=CC(=C7C6)C(=O)NC8=NC9=CC=CC=C9S8)C(=O)O
Synonyms A 1331852, A1331852
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 91 mg/mL (138.12 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.18 mL 75.89 mL 151.79 mL
0.5 mM 3.04 mL 15.18 mL 30.36 mL
1 mM 1.52 mL 7.59 mL 15.18 mL
5 mM 0.3 mL 1.52 mL 3.04 mL
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