Crisaborole (AN2728)

Catalog No.: A12776
PDE4 inhibitor?€?
AN2728 is a topically administered, boron-containing, anti-inflammatory compound that inhibits PDE4 activity and thereby suppresses the release of TNFalpha, IL-12, IL-23 and other cytokines
Grouped product items
Product Name Price Stock Qty
Crisaborole (AN2728) 10mg
$40.00
In stock
Crisaborole (AN2728) 50mg
$55.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription AN2728 is a topically administered, boron-containing, anti-inflammatory compound that inhibits PDE4 activity and thereby suppresses the release of TNFalpha, IL-12, IL-23 and other cytokines
Product Information
Catalog Num A12776
Formula C14H10BNO3
Molecular Weight 251.08
CAS Number 906673-24-3
SMILES B1(C2=C(CO1)C=C(C=C2)OC3=CC=C(C=C3)C#N)O
Synonyms AN 2728, AN-2728
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 47 mg/mL (187.21 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 39.83 mL 199.14 mL 398.28 mL
0.5 mM 7.97 mL 39.83 mL 79.66 mL
1 mM 3.98 mL 19.91 mL 39.83 mL
5 mM 0.8 mL 3.98 mL 7.97 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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