ETP-46464

Catalog No.: A13328
ATR inhibitor
ETP-46464 is a potent and selective inhibitor of ATR with IC50 of 25 nM.
Grouped product items
Product Name Price Stock Qty
ETP-46464 10mg
$140.00
In stock
ETP-46464 25mg
$280.00
In stock
ETP-46464 50mg
$500.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's ETP-46464 has been cited by 1 publications
  • Fu-Xing Gong, .et al. , Nucleic Acids Res, 2021, Sep 20;49(16):9342-9352 PMID: 34403458
  • Biological Activity
    Discription ETP-46464 is a potent and selective inhibitor of ATR with IC50 of 25 nM.
    Targets
    Target Value
    Product Information
    Catalog Num A13328
    Formula C30H22N4O2
    Molecular Weight 470.52
    CAS Number 1345675-02-6
    SMILES CC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3COC2=O)C5=CC6=CC=CC=C6N=C5
    Synonyms ETP46464, ETP 46464
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 6 mg/mL (12.75 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.25 mL 106.27 mL 212.53 mL
    0.5 mM 4.25 mL 21.25 mL 42.51 mL
    1 mM 2.13 mL 10.63 mL 21.25 mL
    5 mM 0.43 mL 2.13 mL 4.25 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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