GO6983

Catalog No.: A13790
PKC inhibitor
GO6983 is a potent protein kinase C (PKC) inhibitor. It reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia/reperfusion injury.
Grouped product items
Product Name Price Stock Qty
GO6983 10mg
$150.00
In stock
GO6983 25mg
$300.00
In stock
GO6983 50mg
$480.00
In stock
GO6983 10mM * 1mL in DMSO
$95.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's GO6983 has been cited by 1 publications
  • Kouki Kawakami, .et al. , Nat Commun, 2022, 13: 487 PMID: 35078997
  • Biological Activity
    Discription GO6983 is a potent protein kinase C (PKC) inhibitor. It reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia/reperfusion injury.
    Targets
    Target Value
    Product Information
    Catalog Num A13790
    Formula C26H26N4O3
    Molecular Weight 442.51
    CAS Number 133053-19-7
    SMILES CN(C)CCCN1C=C(C2=C1C=CC(=C2)OC)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54
    Synonyms Go-6983, Go 6983
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 55 mg/mL (124.29 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.6 mL 112.99 mL 225.98 mL
    0.5 mM 4.52 mL 22.6 mL 45.2 mL
    1 mM 2.26 mL 11.3 mL 22.6 mL
    5 mM 0.45 mL 2.26 mL 4.52 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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