SF1670

Catalog No.: A13475
PTEN inhibitor
SF1670 is a selective PTEN inhibitor (IC50=2 uM). As PTEN-mTOR pathway is critical for controlling the regenerative capacity of corticospinal neurons, PTEN deletion or its inhibitor enhances the regenerative ability of adult corticospinal neurons. Pretreatment with SF1670 augments the efficacy of granulocyte transfusion in a clinically relevant mouse model.
Grouped product items
Product Name Price Stock Qty
SF1670 5mg
$108.00
In stock
SF1670 10mg
$184.00
In stock
SF1670 25mg
$324.00
In stock
SF1670 50mg
$540.00
In stock
SF1670 10mM * 1mL in DMSO
$110.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription SF1670 is a selective PTEN inhibitor (IC50=2 uM). As PTEN-mTOR pathway is critical for controlling the regenerative capacity of corticospinal neurons, PTEN deletion or its inhibitor enhances the regenerative ability of adult corticospinal neurons. Pretreatment with SF1670 augments the efficacy of granulocyte transfusion in a clinically relevant mouse model.
Targets
Target Value
Product Information
Catalog Num A13475
Formula C19H17NO3
Molecular Weight 307.4
CAS Number 345630-40-2
SMILES CC(C)(C)C(=O)NC1=CC2=C(C=C1)C3=CC=CC=C3C(=O)C2=O
Synonyms SF 1670, SF-1670
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO Warmed: 27 mg/mL (87.84 mM)
Water Insoluble
Ethanol Warmed: 1 mg/mL (3.25 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.53 mL 162.65 mL 325.31 mL
0.5 mM 6.51 mL 32.53 mL 65.06 mL
1 mM 3.25 mL 16.27 mL 32.53 mL
5 mM 0.65 mL 3.25 mL 6.51 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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