Tegaserod maleate

Catalog No.: A11743

5-HT antagonist

Tegaserod functions as a motility stimulant, achieving its desired therapeutic effects through activation of the 5-HT4 receptors of the enteric nervous system in the gastrointestinal tract. It also stimulates gastrointestinal motility and the peristaltic reflex, and allegedly reduces abdominal pain. Additionally, tegaserod is a 5-HT2B receptor antagonist.
Grouped product items
Product Name Price Stock Qty
Tegaserod maleate 10mg
$90.00
In stock
Tegaserod maleate 50mg
$280.00
In stock
Tegaserod maleate 100mg
$480.00
In stock
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Biological Activity
Discription Tegaserod functions as a motility stimulant, achieving its desired therapeutic effects through activation of the 5-HT4 receptors of the enteric nervous system in the gastrointestinal tract. It also stimulates gastrointestinal motility and the peristaltic reflex, and allegedly reduces abdominal pain. Additionally, tegaserod is a 5-HT2B receptor antagonist.
Targets
Target Value
Product Information
Catalog Num A11743
Formula C16H23N5O.C4H4O4
Molecular Weight 417.46
CAS Number 189188-57-6
SMILES CCCCCN=C(N)NN/C=C/1\C=NC2=C1C=C(C=C2)OC.C(=C\C(=O)O)\C(=O)O
Synonyms Zelnorm
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 72 mg/mL (172.47 mM)
Water Insoluble
Ethanol 7 mg/mL (16.77 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.95 mL 119.77 mL 239.54 mL
0.5 mM 4.79 mL 23.95 mL 47.91 mL
1 mM 2.4 mL 11.98 mL 23.95 mL
5 mM 0.48 mL 2.4 mL 4.79 mL
Useful Calculator

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